Alpha-nicotinic acetylcholine receptor and tobacco smoke exposure: effects on bronchial hyperresponsiveness in children.

doi:10.1111/j.1399-3038.2011.01222.x

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Article

Alpha-nicotinic acetylcholine receptor and tobacco smoke exposure: effects on bronchial hyperresponsiveness in children.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Feb 2012

Torjussen Tale M, Lødrup Carlsen Karin C, Munthe-Kaas Monica C, Mowinckel Petter, Carlsen Kai-Håkon, Helms Peter J, Gerritsen Jorrit, Whyte Moira K, Lenney Warren, Undlien Dag E, Shianna Kevin V, Zhu Guohua, Pillai Sreekumar G

Abstract excerpt

BACKGROUND: The CHRNA 3 and 5 genes on chromosome 15 encode the alpha subunits of the nicotinic acetylcholine receptor, mediating airway cholinergic activity. Polymorphisms are associated with cigarette smoking, chronic obstructive pulmonary disease, and lung cancer. AIMS: To determine possible associations between CHRNA 3/5 SNP rs8034191 and asthma or lung function in children in one local and one replicate...

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Identifiers

PMID: 22017462
DOI: 10.1111/j.1399-3038.2011.01222.x

Genes

CHRNA3
FEV

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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