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Article

Extragenic suppressors of mar2(sir3) mutations in Saccharomyces cerevisiae.

Genetics - 1 Jun 1990

Lin C I, Livi G P, Ivy J M, Klar A J

Abstract excerpt

The silent mating-type genes (HML and HMR) of Saccharomyces cerevisiae are kept under negative transcriptional control by four trans-acting MAR (or SIR) loci. We have isolated extragenic suppressors of the mar2-1 mutation which, based on genetic complementation tests, define two additional loci involved in regulating the expression of HML and HMR. A strain with the genotype HMLa MAT alpha HMRa mar2-1 is sterile...

Topics

Alleles
Genes, Fungal
Genes, Mating Type, Fungal
Genes, Recessive
Genetic Complementation Test
Phenotype
Saccharomyces cerevisiae
Suppression, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2199314
DOI: 10.1093/genetics/125.2.321
PMCID: PMC1204022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2199314-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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