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Article

Design of a minimal silencer for the silent mating-type locus HML of Saccharomyces cerevisiae.

Nucleic acids research - 1 Dec 2010

Weber Jan M, Ehrenhofer-Murray Ann E

Abstract excerpt

The silent mating-type loci HML and HMR of Saccharomyces cerevisiae contain mating-type information that is permanently repressed. This silencing is mediated by flanking sequence elements, the E- and I-silencers. They contain combinations of binding sites for the proteins Rap1, Abf1 and Sum1 as well as for the origin recognition complex (ORC). Together, they recruit other silencing factors, foremost the...

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Identifiers

PMID: 20699276
DOI: 10.1093/nar/gkq689
PMCID: PMC3001064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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