Article
MGA2 and SPT23 are modifiers of transcriptional silencing in yeast.
Genetics - 1 Nov 2000
Dula M L, Holmes S G
Abstract excerpt
Transcriptional silencing at the HM loci and telomeres in yeast depends on several trans-acting factors, including Rap1p and the Sir proteins. The SUM1-1 mutation was identified by its ability to restore silencing to strains deficient in one or more of these trans-acting factors. The mechanism by which SUM1-1 bypasses the requirement for silencing proteins is not known. We identified four loci that when reduced...
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