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Article

A role for CDC7 in repression of transcription at the silent mating-type locus HMR in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Feb 1991

Axelrod A, Rine J

Abstract excerpt

The mating-type genes at MAT in Saccharomyces cerevisiae are expressed, whereas the same genes located at HML and HMR are transcriptionally repressed. The DNA element responsible for repression at HMR has been termed a silencer and contains an autonomous replication sequence, a binding site for GRFI/RAPI, and a binding site for ABFI. A double-mutant HMR-E silencer that contains single nucleotide substitutions in...

Topics

Crosses, Genetic
Gene Expression Regulation, Fungal
Genes, Fungal
Genes, Mating Type, Fungal
Genes, Suppressor
Genotype
Protein Kinases
Repressor Proteins
Saccharomyces cerevisiae
Suppression, Genetic
Transcription, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1990268
DOI: 10.1128/mcb.11.2.1080-1091.1991
PMCID: PMC359783

Genes

CDC7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1990268-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A role for CDC7 in repression of transcription at the silent mating-type locus HMR in Saccharomyces cerevisiae.PMID 1990268Read ↗

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