Article
Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1990
Johnson L M, Kayne P S, Kahn E S, Grunstein M
Abstract excerpt
Repression of transcription from the silent mating loci (HML alpha and HMRa) is essential for mating ability in Saccharomyces cerevisiae. This silencing is known to require at least five proteins (SIR1, SIR2, SIR3, SIR4, and histone H4) and is accompanied by a change in chromatin structure. We sh...
Topics
- Amino Acid Sequence
- Chromosome Deletion
- Crosses, Genetic
- Fungal Proteins
- Genes, Fungal
- Histones
- Molecular Sequence Data
- Mutation
- Saccharomyces cerevisiae
- Suppression, Genetic
- Transcription, Genetic