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Article

SUM1-1: a suppressor of silencing defects in Saccharomyces cerevisiae.

Genetics - 1 Nov 1991

Laurenson P, Rine J

Abstract excerpt

The repression of transcription of the silent mating-type locus HMRa in the yeast Saccharomyces cerevisiae requires the four SIR proteins, histone H4 and a flanking site designated HMR-E. The SUM1-1 mutation alleviated the need for many of these components in transcriptional repression. In the absence of each of the SIR proteins, SUM1-1 restored repression in MAT alpha strains; thus, SUM1-1 appeared to bypass the...

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Identifiers

PMID: 1752414
DOI: 10.1093/genetics/129.3.685
PMCID: PMC1204736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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