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Article

SUM1-1: a suppressor of silencing defects in Saccharomyces cerevisiae.

Genetics - 1 Nov 1991

Laurenson P, Rine J

Abstract excerpt

The repression of transcription of the silent mating-type locus HMRa in the yeast Saccharomyces cerevisiae requires the four SIR proteins, histone H4 and a flanking site designated HMR-E. The SUM1-1 mutation alleviated the need for many of these components in transcriptional repression. In the absence of each of the SIR proteins, SUM1-1 restored repression in MAT alpha strains; thus, SUM1-1 appeared to bypass the...

Topics

Alleles
Epistasis, Genetic
Genes, Dominant
Genes, Fungal
Genes, Mating Type, Fungal
Genes, Suppressor
Regulatory Sequences, Nucleic Acid
Saccharomyces cerevisiae

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1752414
DOI: 10.1093/genetics/129.3.685
PMCID: PMC1204736

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1752414-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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