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Article

Interspecies variation reveals a conserved repressor of alpha-specific genes in Saccharomyces yeasts.

Genes & development - 15 Jun 2008

Zill Oliver A, Rine Jasper

Abstract excerpt

The mating-type determination circuit in Saccharomyces yeast serves as a classic paradigm for the genetic control of cell type in all eukaryotes. Using comparative genetics, we discovered a central and conserved, yet previously undetected, component of this genetic circuit: active repression of alpha-specific genes in a cells. Upon inactivation of the SUM1 gene in Saccharomyces bayanus, a close relative of...

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Share to Conserved Sequence
Share to Gene Expression Regulation, Fungal
Share to Genes, Mating Type, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Organisms, Genetically Modified

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Share to Sequence Homology, Nucleic Acid

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Source

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Identifiers

PMID: 18559484
DOI: 10.1101/gad.1640008
PMCID: PMC2428066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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