Article
Acetylation regulates monopolar attachment at multiple levels during meiosis I in fission yeast.
EMBO reports - 28 Oct 2011
Kagami Ayano, Sakuno Takeshi, Yamagishi Yuya, Ishiguro Tadashi, Tsukahara Tatsuya, Shirahige Katsuhiko, Tanaka Koichi, Watanabe Yoshinori
Abstract excerpt
In fission yeast, meiotic mono-orientation of sister kinetochores is established by cohesion at the core centromere, which is established by a meiotic cohesin complex and the kinetochore protein Moa1. The cohesin subunit Psm3 is acetylated by Eso1 and deacetylated by Clr6. We show that in meiosis, Eso1 is required for establishing core centromere cohesion during S phase, whereas Moa1 is required for maintaining...
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