Article
Aurora controls sister kinetochore mono-orientation and homolog bi-orientation in meiosis-I.
The EMBO journal - 31 Oct 2007
Hauf Silke, Biswas Ashapurno, Langegger Maria, Kawashima Shigehiro A, Tsukahara Tatsuya, Watanabe Yoshinori
Abstract excerpt
Aurora-B kinases are important regulators of mitotic chromosome segregation, where they are required for the faithful bi-orientation of sister chromatids. In contrast to mitosis, sister chromatids have to be oriented toward the same spindle pole in meiosis-I, while homologous chromosomes are bi-oriented. We find that the fission yeast Aurora kinase Ark1 is required for the faithful bi-orientation of sister...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
