Article
Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I.
Developmental cell - 1 Apr 2003
Rabitsch Kirsten P, Petronczki Mark, Javerzat Jean Paul, Genier Sylvie, Chwalla Barbara, Schleiffer Alex, Tanaka Tomoyuki U, Nasmyth Kim
Abstract excerpt
Halving of the chromosome number during meiosis I depends on the segregation of maternal and paternal centromeres. This process relies on the attachment of sister centromeres to microtubules emanating from the same spindle pole. We describe here the identification of a protein complex, Csm1/Lrs4, that is essential for monoorientation of sister kinetochores in Saccharomyces cerevisiae. Both proteins are present in...
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