Article
Genetic control of susceptibility to infection with Plasmodium chabaudi chabaudi AS in inbred mouse strains.
Genes and immunity - 1 Feb 2012
Laroque A, Min-Oo G, Tam M, Radovanovic I, Stevenson M M, Gros P
Abstract excerpt
To identify genetic effects modulating the blood stage replication of the malarial parasite, we phenotyped a group of 25 inbred mouse strains for susceptibility to Plasmodium chabaudi chabaudi AS infection (peak parasitemia, survival). A broad spectrum of responses was observed, with strains such as C57BL/6J being the most resistant (low parasitemia, 100% survival) and strains such as NZW/LacJ and C3HeB/FeJ being...
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