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Article

Malaria liver stage susceptibility locus identified on mouse chromosome 17 by congenic mapping.

PloS one - 26 Mar 2008

Gonçalves Lígia Antunes, Almeida Paulo, Mota Maria Manuel, Penha-Gonçalves Carlos

Abstract excerpt

Host genetic variants are known to confer resistance to Plasmodium blood stage infection and to control malaria severity both in humans and mice. This work describes the genetic mapping of a locus for resistance to liver stage parasite in the mouse. First, we show that decreased susceptibility to the liver stage of Plasmodium berghei in the BALB/c mouse strain is attributable to intra-hepatic factors and impacts...

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Identifiers

PMID: 18365019
DOI: 10.1371/journal.pone.0001874
PMCID: PMC2267218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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