Article
Mice that are congenic for the char2 locus are susceptible to malaria.
Infection and immunity - 1 Aug 2002
Burt Rachel A, Marshall Vikki M, Wagglen Jamie, Rodda Fleur R, Senyschen Danielle, Baldwin Tracey M, Buckingham Lynn A, Foote Simon J
Abstract excerpt
A major advance has been made towards the positional cloning of char2 (a quantitative trait locus encoding resistance to Plasmodium chabaudi malaria). Mice congenic for the locus have been used to fine map the gene and to prove that char2 plays a significant role in the outcome of malarial infection, independently of other resistance loci.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.