Article
Identification of two cerebral malaria resistance loci using an inbred wild-derived mouse strain.
Proceedings of the National Academy of Sciences of the United States of America - 23 Jul 2002
Bagot Sébastien, Campino Susana, Penha-Gonçalves Carlos, Pied Sylviane, Cazenave Pierre-André, Holmberg Dan
Abstract excerpt
Malaria is a complex infectious disease in which the host/parasite interaction is strongly influenced by host genetic factors. The consequences of plasmodial infections range from asymptomatic to severe complications like the neurological syndrome cerebral malaria induced by Plasmodium falciparum in humans and Plasmodium berghei ANKA in rodents. Mice infected with P. berghei ANKA show marked differences in...
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