Article
Complex genetic control of susceptibility to malaria in mice.
Genes and immunity - 1 Jun 2002
Fortin A, Stevenson M M, Gros P
Abstract excerpt
Malaria is a major infectious disease worldwide, with over 1 million deaths in African children every year. The molecular pathways of pathogenesis of the Plasmodium parasite and the host mechanisms of defense against this infection remain poorly understood. Epidemiological studies, together with linkage analyses in endemic areas have clearly pointed at a genetic component of innate susceptibility and severity of...
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