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Article

Identification of a new malaria susceptibility locus (Char4) in recombinant congenic strains of mice.

Proceedings of the National Academy of Sciences of the United States of America - 11 Sept 2001

Fortin A, Cardon L R, Tam M, Skamene E, Stevenson M M, Gros P

Abstract excerpt

The genetic component of susceptibility to malaria is complex, both in humans and in the mouse model of infection. Two murine loci on chromosomes 8 (Pchr/Char2) and 9 (Char1) have previously been mapped in F(2) crosses, and play an important role in regulating blood parasitemia and survival to infection with Plasmodium chabaudi. These loci explain only part of the interstrain phenotypic variance, and their...

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Identifiers

PMID: 11535821
DOI: 10.1073/pnas.191288998
PMCID: PMC58554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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