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Transcriptional modulator <i>H2A histone family, member Y</i> ( <i>H2AFY</i> ) marks Huntington disease activity in man and mouse

3 Oct 2011

Abstract excerpt

Huntington disease (HD) is a progressive neurodegenerative disease that affects 30,000 individuals in North America. Treatments that slow its relentless course are not yet available, and biomarkers that can reliably measure disease activity and therapeutic response are urgently needed to facilitate their development. Here, we interrogated 119 human blood samples for transcripts associated with HD. We found that...

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PMID: 21969577
DOI: 10.1073/pnas.1104409108

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