Article
Detection of c-Ki-ras gene mutation in paraffin sections of adenocarcinoma and atypical bronchioloalveolar cell hyperplasia of human lung.
Virchows Archiv : an international journal of pathology - 1 Jan 1994
Ohshima S, Shimizu Y, Takahama M
Abstract excerpt
DNA of minute specimens taken from formalin-fixed and paraffin-embedded tissue was used as a template for the polymerase chain reaction (PCR) to examine whether the c-Ki-ras gene is activated in atypical bronchioloalveolar cell hyperplasia (ABH) of human lung. The c-Ki-ras gene was successfully a...
Topics
- Adenocarcinoma
- Adult
- Aged
- Base Sequence
- Bronchi
- DNA Mutational Analysis
- DNA, Neoplasm
- Female
- Genes, ras
- Humans
- Hyperplasia
- Lung Neoplasms
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Point Mutation
- Polymerase Chain Reaction