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Article

Common genetic variants in cell cycle pathway are associated with survival in stage III-IV non-small-cell lung cancer.

Carcinogenesis - 1 Dec 2011

Yin Jikai, Lu Charles, Gu Jian, Lippman Scott M, Hildebrandt Michelle A T, Lin Jie, Stewart David, Spitz Margaret R, Wu Xifeng

Abstract excerpt

Cell cycle progression contributes to the cellular response to DNA-damaging factors, such as chemotherapy and radiation. We hypothesized that the genetic variations in cell cycle pathway genes may modulate treatment responses and affect survival in patients with advanced non-small-cell lung cancer (NSCLC). We genotyped 374 single-nucleotide polymorphisms (SNPs) from 49 cell cycle-related genes in 598 patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21965272
DOI: 10.1093/carcin/bgr217
PMCID: PMC3220611

Genes

CCNB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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