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Article

Potentially functional polymorphisms in DNA repair genes and non-small-cell lung cancer survival: a pathway-based analysis.

Molecular carcinogenesis - 1 Jul 2012

Dong Jing, Hu Zhibin, Shu Yongqian, Pan Shiyang, Chen Wenping, Wang Yi, Hu Lingmin, Jiang Yue, Dai Juncheng, Ma Hongxia, Jin Guangfu, Shen Hongbing

Abstract excerpt

To assess systematically whether potentially functional polymorphisms in DNA repair genes influence the clinical behavior of non-small-cell lung cancer (NSCLC), we examined the impact of a comprehensive panel of 218 signal nucleotide polymorphisms (SNP) in 50 candidate DNA repair genes on overall survival of NSCLC in a case-cohort of 568 lung cancer patients. SNPs associated with lung cancer prognosis primarily...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21739480
DOI: 10.1002/mc.20819

Genes

ATM
ERCC1
ERCC2
MBD4
PMS1
XPC
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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