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Article

Genetic variations in the regulator of G-protein signaling genes are associated with survival in late-stage non-small cell lung cancer.

PloS one - 1 Jan 2011

Dai Jingyao, Gu Jian, Lu Charles, Lin Jie, Stewart David, Chang David, Roth Jack A, Wu Xifeng

Abstract excerpt

The regulator of G-protein signaling (RGS) pathway plays an important role in signaling transduction, cellular activities, and carcinogenesis. We hypothesized that genetic variations in RGS gene family may be associated with the response of late-stage non-small cell lung cancer (NSCLC) patients to chemotherapy or chemoradiotherapy. We selected 95 tagging single nucleotide polymorphisms (SNPs) in 17 RGS genes and...

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Share to Antineoplastic Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21698121
DOI: 10.1371/journal.pone.0021120
PMCID: PMC3117866

Genes

RGS1
RGS12
RGS7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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