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Article

Genetic variants of CHEK1, PRIM2 and CDK6 in the mitotic phase-related pathway are associated with nonsmall cell lung cancer survival.

International journal of cancer - 15 Sept 2021

Mu Rui, Liu Hongliang, Luo Sheng, Patz Edward F, Glass Carolyn, Su Li, Du Mulong, Christiani David C, Jin Lei, Wei Qingyi

Abstract excerpt

The mitotic phase is a vital step in cell division and may be involved in cancer progression, but it remains unclear whether genetic variants in mitotic phase-related pathways genes impact the survival of these patients. Here, we investigated associations between 31 032 single nucleotide polymorphisms (SNPs) in 368 mitotic phase-related pathway genes and overall survival (OS) of patients with nonsmall cell lung...

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Identifiers

PMID: 34058013
DOI: 10.1002/ijc.33702
PMCID: PMC8916708

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