Article
Genetic variants in cell cycle control pathway confer susceptibility to lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2007
Wang Wei, Spitz Margaret R, Yang Hushan, Lu Charles, Stewart David J, Wu Xifeng
Abstract excerpt
PURPOSE: To test the hypothesis that common sequence variants of cell cycle control genes may affect lung cancer predisposition. EXPERIMENTAL DESIGN: We explored lung cancer risk associations of 11 polymorphisms in seven cell cycle genes in a large case-control study including 1,518 Caucasian lung cancer patients and 1,518 controls. RESULTS: When individuals with variant-containing genotypes were compared with...
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