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Article

Potentially functional polymorphisms in cell cycle genes and the survival of non-small cell lung cancer in a Chinese population.

Lung cancer (Amsterdam, Netherlands) - 1 Jul 2011

Ma Hongxia, Chen Jiaping, Pan Shiyang, Dai Juncheng, Jin Guangfu, Hu Zhibin, Shen Hongbing, Shu Yongqian

Abstract excerpt

The cell cycle governs the proliferation and growth of cells and is strictly controlled by some regulators including cyclins, CDKs and CKIs. Germ-line and somatic mutations in cell cycle genes were frequently observed in a subset of cancers including non-small cell lung cancer (NSCLC). In this study, we hypothesized that potentially functional single nucleotide polymorphisms (SNPs) in cell cycle genes may...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21145615
DOI: 10.1016/j.lungcan.2010.11.001

Genes

CCNA1
CCNA2
CCNB1
CCND1
CCND2
CCND3
CCNE1
CCNH
CDK1
CDK2
CDK4
CDK6
CDK7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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