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Article

Sequence and Functional Variation in the HIV-1 Rev Regulatory Axis.

Current HIV research - 1 Jan 2020

Jackson Patrick E H, Dzhivhuho Godfrey, Rekosh David, Hammarskjold Marie-Louise

Abstract excerpt

BACKGROUND: To complete its replication cycle, HIV-1 requires the nucleocytoplasmic export of intron-containing viral mRNAs. This process is ordinarily restricted by the cell, but HIV overcomes the block by means of a viral protein, Rev, and an RNA secondary structure found in all unspliced and incompletely spliced viral mRNAs called the Rev Response Element (RRE). In vivo activity of the Rev-RRE axis requires...

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Share to rev Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 31906839
DOI: 10.2174/1570162X18666200106112842
PMCID: PMC7113094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Sequence and Functional Variation in the HIV-1 Rev Regulatory Axis.PMID 31906839Read ↗

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