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Article

Rev regulates translation of human immunodeficiency virus type 1 RNAs.

The Journal of general virology - 1 May 2009

Groom Harriet C T, Anderson Emma C, Dangerfield John A, Lever Andrew M L

Abstract excerpt

Full-length human immunodeficiency virus type 1 (HIV-1) RNA acts as both mRNA, encoding Gag and Gag-Pol polyproteins, and genomic RNA. Translation of this RNA must be tightly controlled to allow sufficient protein synthesis prior to a switch to particle production. The viral protein Rev stimulates nuclear export of unspliced HIV-1 RNAs containing the Rev response element, but may also stimulate translation of...

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Source

Identifiers

PMID: 19264599
DOI: 10.1099/vir.0.007963-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Rev regulates translation of human immunodeficiency virus type 1 RNAs.PMID 19264599Read ↗

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Identification of a cellular factor that modulates HIV-1 programmed ribosomal frameshifting.Semantic proximity Read ↗

Nucleocytoplasmic transport of the Rev protein of human immunodeficiency virus type 1 is dependent on the activation domain of the protein.Semantic proximity Read ↗

Functional domains of the HIV-1 rev gene required for trans-regulation and subcellular localization.Semantic proximity Read ↗

HIV Rev Assembly on the Rev Response Element (RRE): A Structural PerspectiveSemantic proximity Read ↗

The HIV-1 Rev protein enhances encapsidation of unspliced and spliced, RRE-containing lentiviral vector RNA.Semantic proximity Read ↗

An AUG codon upstream of rev and env open reading frames ensures optimal translation of the simian immunodeficiency virus Env protein.Semantic proximity Read ↗

A small element from the Mason-Pfizer monkey virusgenome makes human immunodeficiency virus type 1 expression and replicationRev-independent.Semantic proximity Read ↗

Identification of a Heterogeneous Nuclear Ribonucleoprotein-recognition Region in the HIV Rev ProteinSemantic proximity Read ↗

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