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Mismatch repair causes the dynamic release of an essential DNA polymerase from the replication fork

30 Sept 2011

Abstract excerpt

Mismatch repair (MMR) corrects DNA polymerase errors occurring during genome replication. MMR is critical for genome maintenance, and its loss increases mutation rates several hundred fold. Recent work has shown that the interaction between the mismatch recognition protein MutS and the replication processivity clamp is important for MMR in Bacillus subtilis. To further understand how MMR is coupled to DNA...

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PMID: 21958350
DOI: 10.1111/j.1365-2958.2011.07841.x

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