Article
Generation of a conditional null allele of Lbx1.
Genesis (New York, N.Y. : 2000) - 1 Oct 2011
Watanabe Shuichi, Matsushita Shoko, Hayasaka Michiko, Hanaoka Kazunori
Abstract excerpt
The homeobox gene Lbx1 not only plays critical roles in myogenesis and neurogenesis during embryonic development but is also expressed in activated satellite cells of adult mice. To address the potential postnatal functions of Lbx1, we generated conditional Lbx1-null mice using the Cre-loxP system. We generated a mouse in which Exon 2 of Lbx1 was floxed (Lbx1flox/flox), followed by cross-breeding between the...
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