Article
Generation of a conditionally null allele of the laminin alpha1 gene.
Genesis (New York, N.Y. : 2000) - 1 Oct 2005
Alpy F, Jivkov I, Sorokin L, Klein A, Arnold C, Huss Y, Kedinger M, Simon-Assmann P, Lefebvre O
Abstract excerpt
Laminins are heterotrimeric glycoproteins of the basement membranes. Laminin 1 (alpha1, beta1, gamma1) is the major laminin expressed during early mouse embryogenesis. To gain access to the physiological function of laminin alpha1 chain, we developed a conditionally null allele of its encoding ge...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.