Article
Lbx1 is required for muscle precursor migration along a lateral pathway into the limb.
Development (Cambridge, England) - 1 Jan 2000
Gross M K, Moran-Rivard L, Velasquez T, Nakatsu M N, Jagla K, Goulding M
Abstract excerpt
In mammalian embryos, myogenic precursor cells emigrate from the ventral lip of the dermomyotome and colonize the limbs, tongue and diaphragm where they differentiate and form skeletal muscle. Previous studies have shown that Pax3, together with the c-Met receptor tyrosine kinase and its ligand Scatter Factor (SF) are necessary for the migration of hypaxial muscle precursors in mice. Lbx1 and Pax3 are...
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