Article
The homeobox containing gene Lbx1 is required for correct dorsal-ventral patterning of the neural tube.
Journal of neurochemistry - 1 Aug 2002
Krüger Markus, Schäfer Konstanze, Braun Thomas
Abstract excerpt
The specification of distinct classes of neurones in the neural tube is governed by extracellular signals and transcriptional mediators including neurogenic bHLH- and homeobox-containing genes. Despite recent insights in the transcriptional code that controls generation of neuronal subtypes in the dorsal neural tube, the mechanisms that underlie regional identity in dorsal and lateral regions of the mammalian...
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