Article
Generation of mice with a conditional Lbh null allele.
Genesis (New York, N.Y. : 2000) - 1 Jul 2013
Lindley Linsey E, Briegel Karoline J
Abstract excerpt
Limb bud and heart (LBH) is a developmentally expressed, tissue-specific transcription cofactor in vertebrates that acts in the WNT signaling pathway, a genetic program critical for embryogenesis and adult tissue homeostasis. Aberrant gain-of-function of LBH is implicated in both human congenital disease and cancer. The normal physiological function of LBH has remained elusive owing to a lack of genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
