Article
A targeted association study of immunity genes and networks suggests novel associations with placental malaria infection.
PloS one - 1 Jan 2011
Sikora Martin, Laayouni Hafid, Menendez Clara, Mayor Alfredo, Bardaji Azucena, Sigauque Betuel, Netea Mihai G, Casals Ferran, Bertranpetit Jaume
Abstract excerpt
A large proportion of the death toll associated with malaria is a consequence of malaria infection during pregnancy, causing up to 200,000 infant deaths annually. We previously published the first extensive genetic association study of placental malaria infection, and here we extend this analysis considerably, investigating genetic variation in over 9,000 SNPs in more than 1,000 genes involved in immunity and...
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