Article
Neurexin-neuroligin adhesions capture surface-diffusing AMPA receptors through PSD-95 scaffolds.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 Sept 2011
Mondin Magali, Labrousse Virginie, Hosy Eric, Heine Martin, Tessier Béatrice, Levet Florian, Poujol Christel, Blanchet Christophe, Choquet Daniel, Thoumine Olivier
Abstract excerpt
The mechanisms governing the recruitment of functional glutamate receptors at nascent excitatory postsynapses following initial axon-dendrite contact remain unclear. We examined here the ability of neurexin/neuroligin adhesions to mobilize AMPA-type glutamate receptors (AMPARs) at postsynapses through a diffusion/trap process involving the scaffold molecule PSD-95. Using single nanoparticle tracking in primary...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
