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Article

AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions.

Nature communications - 23 Aug 2021

Watson Jake F, Pinggera Alexandra, Ho Hinze, Greger Ingo H

Abstract excerpt

AMPA receptor (AMPAR) abundance and positioning at excitatory synapses regulates the strength of transmission. Changes in AMPAR localisation can enact synaptic plasticity, allowing long-term information storage, and is therefore tightly controlled. Multiple mechanisms regulating AMPAR synaptic anchoring have been described, but with limited coherence or comparison between reports, our understanding of this...

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Share to CA1 Region, Hippocampal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Neurological

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Share to Receptors, AMPA

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Source

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Identifiers

PMID: 34426577
DOI: 10.1038/s41467-021-25281-4
PMCID: PMC8382838

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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