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Article

Transsynaptic signaling by activity-dependent cleavage of neuroligin-1.

Neuron - 18 Oct 2012

Peixoto Rui T, Kunz Portia A, Kwon Hyungbae, Mabb Angela M, Sabatini Bernardo L, Philpot Benjamin D, Ehlers Michael D

Abstract excerpt

Adhesive contact between pre- and postsynaptic neurons initiates synapse formation during brain development and provides a natural means of transsynaptic signaling. Numerous adhesion molecules and their role during synapse development have been described in detail. However, once established, the mechanisms of adhesive disassembly and its function in regulating synaptic transmission have been unclear. Here, we...

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Identifiers

PMID: 23083741
DOI: 10.1016/j.neuron.2012.07.006
PMCID: PMC3783515

Genes

MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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