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Article

Pre-post synaptic alignment through neuroligin-1 tunes synaptic transmission efficiency.

eLife - 25 Jul 2018

Haas Kalina T, Compans Benjamin, Letellier Mathieu, Bartol Thomas M, Grillo-Bosch Dolors, Sejnowski Terrence J, Sainlos Matthieu, Choquet Daniel, Thoumine Olivier, Hosy Eric

Abstract excerpt

The nanoscale organization of neurotransmitter receptors regarding pre-synaptic release sites is a fundamental determinant of the synaptic transmission amplitude and reliability. How modifications in the pre- and post-synaptic machinery alignments affects synaptic currents, has only been addressed with computer modelling. Using single molecule super-resolution microscopy, we found a strong spatial correlation...

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Share to Cell Adhesion Molecules, Neuronal
Share to Excitatory Postsynaptic Potentials

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neurons

Share to Receptors, AMPA

Share to Synapses

Share to Synaptic Transmission

Source

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Identifiers

PMID: 30044218
DOI: 10.7554/eLife.31755
PMCID: PMC6070337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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