Article
CaMKII phosphorylation of neuroligin-1 regulates excitatory synapses.
Nature neuroscience - 1 Jan 2014
Bemben Michael A, Shipman Seth L, Hirai Takaaki, Herring Bruce E, Li Yan, Badger John D, Nicoll Roger A, Diamond Jeffrey S, Roche Katherine W
Abstract excerpt
Neuroligins are postsynaptic cell adhesion molecules that are important for synaptic function through their trans-synaptic interaction with neurexins (NRXNs). The localization and synaptic effects of neuroligin-1 (NL-1, also called NLGN1) are specific to excitatory synapses with the capacity to enhance excitatory synapses dependent on synaptic activity or Ca(2+)/calmodulin kinase II (CaMKII). Here we report that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.