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Article

Novel pentameric structure of the diarrhea-inducing region of the rotavirus enterotoxigenic protein NSP4.

Journal of virology - 1 Dec 2011

Chacko Anita R, Arifullah Mohammed, Sastri Narayan P, Jeyakanthan Jeyaraman, Ueno Go, Sekar Kanagaraj, Read Randy J, Dodson Eleanor J, Rao Durga C, Suguna Kaza

Abstract excerpt

A novel pentameric structure which differs from the previously reported tetrameric form of the diarrhea-inducing region of the rotavirus enterotoxin NSP4 is reported here. A significant feature of this pentameric form is the absence of the calcium ion located in the core region of the tetrameric structures. The lysis of cells, the crystallization of the region spanning residues 95 to 146 of NSP4 (NSP4(95-146)) of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21917949
DOI: 10.1128/JVI.00349-11
PMCID: PMC3209389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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