Article
Structure analysis of the fourth transmembrane domain of Nramp1 in model membranes.
Biochimica et biophysica acta - 1 Jun 2008
Xue Rong, Wang Shuo, Qi Haiyan, Song Yuande, Wang Chunyu, Li Fei
Abstract excerpt
Nramp1 (natural resistance-associated macrophage protein 1) is an integral membrane protein with 12 putative transmembrane domains. As a proton-coupled divalent metal cation transporter, it is involved in defense against intracellular pathogens. Disease-causing mutation in Nramp1 occurring at gly...
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