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Expression and purification of coronavirus envelope proteins using a modified β-barrel construct.

Protein expression and purification - 1 Sept 2012

Parthasarathy Krupakar, Lu Huang, Surya Wahyu, Vararattanavech Ardcharaporn, Pervushin Konstantin, Torres Jaume

Abstract excerpt

Coronavirus envelope (E) proteins are short (~100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to...

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Identifiers

PMID: 22819936
DOI: 10.1016/j.pep.2012.07.005
PMCID: PMC7129850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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