Article
Analysis of the stability and function of nucleoplasmin through cysteine mutants.
Archives of biochemistry and biophysics - 15 May 2005
Arnan Carme, Prieto Cèlia, Chiva Manel, Salvany Lara, Ausió Juan, Subirana Juan A, Saperas Núria
Abstract excerpt
Xenopus laevis nucleoplasmin is a pentameric nuclear chaperone. The relation between the structure and the multifunctional aspects of the molecule has not yet been clearly established. In the course of analysing a C-terminally His-tagged recombinant version of the region equivalent to the trypsin resistant core (r-NP142) of the molecule, we found that this domain exhibited a substantially decreased...
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