Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional Diversity of Heat-labile Toxins (LT) Produced by Enterotoxigenic Escherichia coli

7 Dec 2010

Abstract excerpt

Heat-labile toxins (LTs) have ADP-ribosylation activity and induce the secretory diarrhea caused by enterotoxigenic Escherichia coli (ETEC) strains in different mammalian hosts. LTs also act as adjuvants following delivery via mucosal, parenteral, or transcutaneous routes. Previously we have shown that LT produced by human-derived ETEC strains encompass a group of 16 polymorphic variants, including the reference...

Source

Identifiers

PMID: 21135101
DOI: 10.1074/jbc.m110.173682

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Diversity of Heat-labile Toxins (LT) Produced by Enterotoxigenic Escherichia coliPMID 21135101Read ↗

Functional and immunological characterization of a natural polymorphic variant of a heat-labile toxin (LT-I) produced by enterotoxigenic<i>Escherichia coli</i>(ETEC)Semantic proximity Read ↗

Heat-Stable Enterotoxins of Enterotoxigenic Escherichia coli and Their Impact on Host ImmunitySemantic proximity Read ↗

Allele variants of enterotoxigenic Escherichia coli heat-labile toxin are globally transmitted and associated with colonization factors.Semantic proximity Read ↗

Genetic diversity of heat-labile toxin expressed by enterotoxigenic Escherichia coli strains isolated from humans.Semantic proximity Read ↗

Molecular determinants of enterotoxigenic <i>Escherichia coli</i> heat-stable toxin secretion and deliverySemantic proximity Read ↗

Specificity of <em>Escherichia coli</em> Heat-Labile Enterotoxin Investigated by Single-Site Mutagenesis and CrystallographySemantic proximity Read ↗

Identification of new heat-stable (STa) enterotoxin allele variants produced by human enterotoxigenic Escherichia coli (ETEC).Semantic proximity Read ↗

Confronting Challenges to Enterotoxigenic Escherichia coli Vaccine DevelopmentSemantic proximity Read ↗

Weapons of mass destruction: virulence factors of the global killer Enterotoxigenic<i>Escherichia coli</i>Semantic proximity Read ↗

Targeting Enterotoxins: Advancing Vaccine Development for Enterotoxigenic Escherichia coli ETECSemantic proximity Read ↗

Analysis and modeling of heat-labile enterotoxins of Escherichia coli suggests a novel space with insights into receptor preference.Semantic proximity Read ↗

Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.