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Article

Role of glutathione-S-transferase (GST) polymorphisms in patients with advanced Hodgkin lymphoma: results from the HD2000 GISL trial.

Leukemia & lymphoma - 1 Mar 2012

Morabito Fortunato, Hohaus Stefan, Mammi Corrado, Marcheselli Luigi, Gentile Massimo, Merli Francesco, Montanini Antonella, Stelitano Caterina, La Sala Antonio, Scalone Renato, Voso Maria Teresa, Luminari Stefano, Iannitto Emilio, Gobbi Paolo, Federico Massimo

Abstract excerpt

Polymorphisms of the Glutathione-S Transferase (GST) family may influence the prognosis in lymphoma patients. We aimed to validate the impact of GSTT1 and GSTM1 deletions and of the GSTP1Ile105Val polymorphism on outcome and toxicity in 140 patients with advanced Hodgkin's lymphoma enrolled in the prospective multicenter HD2000-GISL trial, comparing ABVD, BEACOPP and CEC regimens. Carriers of the GSTP1Ile105Val...

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Source

Identifiers

PMID: 21916526
DOI: 10.3109/10428194.2011.623254

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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