Article
Clinical implications of glutathione S-transferase genotyping in patients with diffuse large B-cell lymphoma.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Atanaskovic Lavinika, Cikota-Aleksic Bojana, Tarabar Olivera, Trimcev Jovana, Zivanovic-Ivic Andelina, Marjanovic Slobodan, Magic Zvonko
Abstract excerpt
PURPOSE: Polymorphic deletions in glutathione S-transferase (GST) genes are recognized as a risk factor for lymphoma, other hematological and non-hematological malignancies. The purpose of the present study was to investigate whether deletions of GSTT1 and GSTM1 as well as GSTP1 Ile- 105Val single nucleotide polymorphism influence clinical presentation, response to therapy and outcome in patients with diffuse...
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