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Article

Polymorphisms of glutathione S-transferase mu 1, theta 1, and pi 1 genes and prognosis in Hodgkin lymphoma.

Leukemia & lymphoma - 1 Dec 2010

Lourenço Gustavo J, Lorand-Metze Irene, Delamain Marcia T, Miranda Eliana C M, Kameo Rodolfo, Metze Konradin, Lima Carmen S P

Abstract excerpt

We examined the influence of the glutathione S-transferase mu 1 (GSTM1), theta 1 (GSTT1), and pi 1 (GSTP1) polymorphisms, which are involved in the metabolism of alkylating agents and anthracyclines, on the outcome of patients with Hodgkin lymphoma (HL) treated with conventional chemotherapy. Genomic DNA from 125 consecutive cases was analyzed by polymerase chain reaction and enzymatic digestion for polymorphism...

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Source

Identifiers

PMID: 20977336
DOI: 10.3109/10428194.2010.527402

Genes

GSTT1
GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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