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Article

Glutathione S-transferase P1 genotype and prognosis in Hodgkin's lymphoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2005

Hohaus Stefan, Di Ruscio Annalisa, Di Febo Annalaura, Massini Giuseppina, D'Alo' Francesco, Guidi Francesco, Mansueto Giovanna, Voso Maria Teresa, Leone Giuseppe

Abstract excerpt

PURPOSE: Glutathione S-transferase P1 (GSTP1) is a member of the GST enzyme superfamily that is important for the detoxification of several cytotoxic drugs and their by-products. A single nucleotide polymorphism results in the substitution of isoleucine (Ile) to valine (Val) at codon 105, causing a metabolically less active variant of the enzyme. We assessed the impact of the GSTP1 codon 105 genotype on treatment...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15788664
DOI: 10.1158/1078-0432.CCR-04-1250

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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