Article
RGK family G-domain:GTP analog complex structures and nucleotide-binding properties.
Journal of molecular biology - 21 Oct 2011
Sasson Yehezkel, Navon-Perry Leehee, Huppert Dan, Hirsch Joel A
Abstract excerpt
The RGK family of small G-proteins, including Rad, Gem, Rem1, and Rem2, is inducibly expressed in various mammalian tissues and interacts with voltage-dependent calcium channels and Rho kinase. Many questions remain regarding their physiological roles and molecular mechanism. Previous crystallographic studies reported RGK G-domain:guanosine di-phosphate structures. To test whether RGK proteins undergo a...
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