Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive structural and substrate specificity classification of the Saccharomyces cerevisiae methyltransferome.

PloS one - 1 Jan 2011

Wlodarski Tomasz, Kutner Jan, Towpik Joanna, Knizewski Lukasz, Rychlewski Leszek, Kudlicki Andrzej, Rowicka Maga, Dziembowski Andrzej, Ginalski Krzysztof

Abstract excerpt

Methylation is one of the most common chemical modifications of biologically active molecules and it occurs in all life forms. Its functional role is very diverse and involves many essential cellular processes, such as signal transduction, transcriptional control, biosynthesis, and metabolism. Here, we provide further insight into the enzymatic methylation in S. cerevisiae by conducting a comprehensive structural...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catalytic Domain
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Fungal

Share to Methylation

Share to Methyltransferases

Share to Multigene Family

Share to Proteome

Share to RNA, Fungal

Source

Open in PubMed Open full text

Identifiers

PMID: 21858014
DOI: 10.1371/journal.pone.0023168
PMCID: PMC3153492

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive structural and substrate specificity classification of the Saccharomyces cerevisiae methyltransferome.PMID 21858014Read ↗

Design of allele-specific protein methyltransferase inhibitors.Semantic proximity Read ↗

miCLIP-MaPseq Identifies Substrates of Radical SAM RNA-Methylating Enzyme Using Mechanistic Cross-Linking and Mismatch Profiling.Semantic proximity Read ↗

Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.Semantic proximity Read ↗

Functional characterization of the YmcB and YqeV tRNA methylthiotransferases of Bacillus subtilis.Semantic proximity Read ↗

The m6A methyltransferase Ime4 epitranscriptionally regulates triacylglycerol metabolism and vacuolar morphology in haploid yeast cells.Semantic proximity Read ↗

Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase.Semantic proximity Read ↗

Epigenetic engineering of yeast reveals dynamic molecular adaptation to methylation stress and genetic modulators of specific DNMT3 family membersSemantic proximity Read ↗

Profiling the compendium of changes in Saccharomyces cerevisiae due to mutations that alter availability of the main methyl donor S-Adenosylmethionine.Semantic proximity Read ↗

Sequence-structure-function relationships of Tgs1, the yeast snRNA/snoRNA cap hypermethylase.Semantic proximity Read ↗

A putative role for Mrx3 and Fmp10 in regulating yeast mitochondrial acyl-CoA thioesters.Semantic proximity Read ↗

Structural and functional mapping of Rtg2p determinants involved in retrograde signaling and aging of Saccharomyces cerevisiae.Semantic proximity Read ↗

Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.